Mary G Leonard Selected Research

sovateltide

8/2013	Endothelin B receptor agonist, IRL-1620, enhances angiogenesis and neurogenesis following cerebral ischemia in rats.
6/2012	Endothelin B receptor agonist, IRL-1620, provides long-term neuroprotection in cerebral ischemia in rats.
10/2011	Endothelin B receptor agonist, IRL-1620, reduces neurological damage following permanent middle cerebral artery occlusion in rats.
11/2009	Repeated administration of ET(B) receptor agonist, IRL-1620, produces tachyphylaxis only to its hypotensive effect.

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Mary G Leonard Research Topics

Disease

3	Brain Ischemia (Cerebral Ischemia) 08/2013 - 10/2011
3	Infarction (Infarctions) 08/2013 - 10/2011
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 08/2013 - 10/2011
1	Hyperalgesia 10/2016
1	Postoperative Pain 10/2016
1	Brain Edema (Cerebral Edema) 06/2012
1	Ischemic Stroke 10/2011
1	Hypotension (Low Blood Pressure) 11/2009
1	Carcinoma (Carcinomatosis) 11/2009

Drug/Important Bio-Agent (IBA)

4	sovateltideIBA 08/2013 - 11/2009
3	Endothelin B ReceptorIBA 08/2013 - 10/2011
2	Endothelin-1 (Endothelin 1)IBA 08/2013 - 10/2011
1	centhaquineIBA 10/2016
1	Endothelin A ReceptorIBA 06/2012
1	Endothelin Receptors (Endothelin Receptor)IBA 06/2012
1	Superoxide DismutaseIBA 10/2011
1	Endothelins (Endothelin)IBA 10/2011
1	Glutathione (Reduced Glutathione)IBA 10/2011
1	Malondialdehyde (Propanedial)IBA 10/2011
1	AntioxidantsIBA 10/2011
1	Proteins (Proteins, Gene)FDA Link 10/2011
1	BQ 788IBA 10/2011

Therapy/Procedure

1	Ambulatory Surgical Procedures (Outpatient Surgery) 10/2016
1	Intravenous Injections 08/2013
1	Therapeutics 10/2011